Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study.

Clin Epigenetics · 2021 · PMC8088646 · PMID 33933144

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did not reach statistical significanceno p-value reported

These genes did not reach statistical significance in Analysis 3 , which had the smallest population which compared DNA methylation patterns in 73 individuals with T1DM-ESKD (transplant only) to 73 individuals, matched, with T1DM.

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nominally significantno p-value reported

We confirmed nominally significant association with kidney function at the CUX1 , PTPRN2 and SEPTIN9 locus and with kidney function decline at AFF3 , HDAC4 and SEPTIN9 regions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.