Clinical and Radiologic Disease Activity in Pregnancy and Postpartum in MS.

Neurol Neuroimmunol Neuroinflamm · 2021 · PMC8105896 · PMID 33608303

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1200

boldest claim

The sentences

showed a trendp < 0.10so close (0.05 < p ≤ 0.1)

However, both relapses during pregnancy, and not exclusively breastfeeding, showed a trend toward increased odds of new Gd+ lesions in the first trimester postpartum (0.05 < p < 0.10).

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did not reach statistical significancep = 0.12not close (p > 0.1)

In sensitivity analyses, excluding pregnancies before 2010 did not affect the results; however, excluding pregnancies in women treated with fingolimod or natalizumab before conception (N = 24) resulted in a lower ARR (0.50 [0.30–0.82]) in the first trimester postpartum; this did not reach statistical significance compared with the year prepregnancy ( p = 0.12).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.