Retreatment in locally recurrent nasopharyngeal carcinoma: Current status and perspectives.

Cancer Commun (Lond) · 2021 · PMC8118589 · PMID 33955719

Europe PMC DOI

hedged sentences

0.1640

closest p · 3.3× alpha

0.2290

boldest claim

The sentences

showed a trendP = 0.164not close (p > 0.1)

The median local failure‐free survival (LFFS) showed a trend in favor of hyperfractionation (28.2 vs. 16.6 months, P = 0.164), though there was no significant difference in overall survival.

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failed to reach statistical significanceP = 0.229not close (p > 0.1)

When compared with the group given 60 Gy 10 ‐70 Gy 10 doses, the local salvage rate in those given <60 Gy was significantly inferior ( P = 0.001), but the superiority in local control of those given >70 Gy failed to reach statistical significance ( P = 0.229).

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marginally significantno p-value reported

Grade 3 and above late toxicities were similar, with treatment‐related hemorrhage showing a marginally significant reduction in the group receiving hyperfractionated irradiation.

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a decreasing trendno p-value reported

The 5‐year local control rates similarly show a decreasing trend with increasing rT stage.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.