The Effect of Sodium Iodide on Stromal Loading, Distribution and Degradation of Riboflavin in a Rabbit Model of Transepithelial Corneal Crosslinking.

Clin Ophthalmol · 2021 · PMC8123948 · PMID 34007152

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0950

boldest claim

The sentences

highly significantP < 0.001actually significant

The ANOVA detected highly significant main effects ( P < 0.001) of both Riboflavin Formulation and Time.

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did not reach statistical significanceP = 0.095so close (0.05 < p ≤ 0.1)

While the difference did not reach statistical significance, a trend was observed (P = 0.095).

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showed a trendno p-value reported

The ANOVA of the baseline-subtracted grades throughout UVA exposure showed a trend towards less degradation over time with the NaI-containing formulation, but the difference did not reach significance ( P = 0.12) Mean riboflavin concentration in the corneal stroma after the procedure and sacrifice was comparable in eyes treated with either formulation (NaI riboflavin: 49.7±11.3 μg/g; NaI-free riboflavin: 48.3 ± 8.2 μg/g) ( Figure 4A and Table S3 ).

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