The Arp2/3 Inhibitory Protein Arpin Is Required for Intestinal Epithelial Barrier Integrity.

An overall comparison between control and UC tissues showed a trend toward lower arpin levels in UC tissue that was non-significant ( Figure 4E ).

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Western blot analyses of tissue samples from UC patients and patients undergoing colon surgery who did not suffer from inflammatory bowel diseases revealed that arpin was differently expressed in colon tissue samples of UC patients with a tendency toward lower levels compared to controls that did not reach statistical significance due to the high variation ( Figures 4A,B ).

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