Multi-Site Tumour Sampling Improves the Detection of Intra-Tumour Heterogeneity in Oral and Oropharyngeal Squamous Cell Carcinoma.

Front Med (Lausanne) · 2021 · PMC8141800 · PMID 34041255

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a significant trendP = 0.05actually significant

Among the multi-site sampling blocks, the average positivity rate differed significantly ( P < 0.05) in 17 (65.38%) tumours, whereas a significant trend ( P = 0.05) was observed in 1 (3.85%) tumour.

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did not reach statistical significanceP > 0.05actually significant

Moreover, the detection density of perineural permeation was higher in the MSTS than RS specimens, although this difference did not reach statistical significance (2.00 vs. 1.07 times/cm 2 ; P > 0.05).

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