Clinical spectrum of high-titre GAD65 antibodies.

Patients with epilepsy had the lowest median CSF anti-GAD65 titre (2.5 nmol/L) and the lowest frequency of elevated CSF IgG index (0/22, 0%) among core disease manifestations, but these differences did not reach statistical significance (p=0.10 and p=0.17, respectively).

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Epilepsy showed a trend toward less cerebrospinal fluid inflammation On review of laboratory results ( table 1 ), median serum and cerebrospinal fluid (CSF) anti-GAD65 titre did not differ significantly across core manifestations of GAD65 neurological autoimmunity.

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