Selective vulnerability to atrophy in sporadic Creutzfeldt-Jakob disease.

54 Although it did not survive correction for multiple comparisons, sCJD participants with ataxia compared with those without ataxia showed a trend toward greater left posterior cerebellar atrophy (not shown), which is consistent with a previous finding of a correlation between cerebellar atrophy and ataxia in E200K genetic prion disease. 6 Perhaps a larger sample size is needed to show this effect in sCJD.

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These differences, however, did not reach statistical significance, which might be due to the relatively small sample size.

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