The short-term safety and efficacy of TANDEM microspheres of various sizes and doxorubicin loading concentrations for hepatocellular carcinoma treatment.

Although the finding did not reach statistical significance, half-load doxorubicin microspheres may cause less liver damage than full-loaded doxorubicin microspheres.

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Larger microsphere size (100 μm) and lower doxorubicin loading (half-loaded) showed a trend toward fewer procedure-related complications, post-embolization syndrome, SIR complications, and abdominal pain and fever.

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