CD163 increased at NOR; however, this marker did not reach statistical significance ( p = 0.069; REC 1.0 × 10 6 ± 650,929.7 pg/mL; NOR 1.2 × 10 6 ± 794,388.1 pg/mL; mean difference 174,283.6 pg/mL; 95% CI [11,188, 337,379.3]) ( Figure 1 d).
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The sentences
a statistical trendp = 0.069
Moreover, a statistical trend was found for CD163 ( p = 0.069).
Nonetheless, it may be possible that IL-1ß failed to reach statistical significance due to the presence of IL-10 and IL-1RA, which antagonize the secretion of IL-1ß [ 52 , 53 ]. 5.