Do Salivary Bypass Tubes Reduce the Risk of Pharyngocutaneous Fistula after Laryngopharyngectomy-A Systematic Review and Meta-Analysis.

Cancers (Basel) · 2021 · PMC8201015 · PMID 34204054

Europe PMC DOI

hedged sentences

0.0050

closest p · 0.1× alpha

0.0570

boldest claim

The sentences

highly significantp = 0.005actually significant

In particular, with the exclusion of studies with salivary tubes applied in less than 20% of cases, heterogeneity (I 2 = 57%) could be improved, reaching finally a highly significant result for the meta-analysis (OR 0.42; 95% CI 0.23–0.78; p = 0.005).

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an overall trendp = 0.057so close (0.05 < p ≤ 0.1)

There was an overall trend towards lower PCF rates when using SBTs (22.2% vs. 35.3%; p = 0.057).

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a clear trendno p-value reported

Although the data failed primarily to reach statistical significance, there is a clear trend towards a more favorable outcome in patients with inserted salivary bypass tubes.

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failed to reach statistical significanceno p-value reported

The data indicated a trend towards less PCF formation in patients with insertion of a salivary tube, but the difference had failed to reach statistical significance ( Figure 3 A).

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