Toxicity Profiles and Survival Outcomes Among Patients With Nonmetastatic Nasopharyngeal Carcinoma Treated With Intensity-Modulated Proton Therapy vs Intensity-Modulated Radiation Therapy.

JAMA Netw Open · 2021 · PMC8214161 · PMID 34143193

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a significant trendno p-value reported

IMPT treatment appeared to be associated with a significant trend of lower grades of specific acute AEs, including dysphagia, fatigue, xerostomia, dysgeusia, oral mucositis, weight loss, and hoarseness (eTable 2 in the Supplement ).

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did not reach statistical significanceno p-value reported

The cumulative incidences of acute and chronic grade 3 AEs were both numerically lower in the IMPT group than the IMRT group, although the differences did not reach statistical significance.

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