Thalamic Deep Brain Stimulation for Spasmodic Dysphonia: A Phase I Prospective Randomized Double-Blind Crossover Trial.

Neurosurgery · 2021 · PMC8223243 · PMID 33862624

Europe PMC DOI

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a strong trendno p-value reported

Blinded DBS produced a strong trend toward improved quality of life and objective quality of voice despite the small sample size.

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did not reach statistical significanceno p-value reported

Every patient reported an improvement in quality of life ( P = .07) and had an improvement in quality of their voice ( P = .06) when their blinded DBS was “on” versus “off.” The trend did not reach statistical significance with the small sample size.

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