Automatic positive airway pressure for obstructive sleep apnea in heart failure with reduced ejection fraction.

Clin Res Cardiol · 2021 · PMC8238771 · PMID 32651657

Europe PMC DOI

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showed a trendno p-value reported

Additional primary endpoints peak VO 2 and VO 2 -AT showed a trend in increase in the APAP group.

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failed to reach statistical significanceno p-value reported

The importance of device use in realizing the beneficial effects of APAP was indicated in our study by the fact that the per-protocol analysis showed a significant improvement in percent-predicted peak VO 2 in the APAP group, but a secondary analysis including patients with exercise capacity data at only 3 months failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.