Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology.

Although differences in cell infiltration in lung parenchyma between WT and Daf -/- mice were not significant, there was a clear trend of increased levels in WT mice ( Fig 3E ).

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compared to that observed in WT, that however, did not reach statistical significance due to the variations within the 5 animals analyzed per condition ( Fig 5C ).

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The potent proinflammatory cytokine tumor necrosis factor (TNF)-α showed an overall trend of being decreased in Daf -/- mice, being significantly lower at 9 d.p.i.

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