Ageing-associated changes in DNA methylation in X and Y chromosomes.

Epigenetics Chromatin · 2021 · PMC8254238 · PMID 34215292

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a strong trendno p-value reported

For the X chromosome, we did not observe a strong trend towards hyper- or hypomethylation.

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a clear trendno p-value reported

In contrast, the Y chromosomal age-associated CpGs were enriched in gene bodies, and showed a clear trend towards hypermethylation with age.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.