Given the subtle effects, there may not be significant differences between the single mutants and WT, but I think the strength of the results in Figure 4 and 5 still make the most important contribution. 2.
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NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination.
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The sentences
I agree its a strong trend, but fails to meet significance due to presumably variability.
So stating that there was a doubling of the ChIP signal that failed to reach statistical significance would be more accurate.