Barely Significant
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Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling.

PLoS Pathog · 2021 · PMC8289045 · PMID 34280251

2
hedged sentences
0.0518
closest p · 1.0× alpha
0.0518
boldest claim

The sentences

approaching significancep = 0.0518so close (0.05 < p ≤ 0.1)
On the other hand, we observed positive enrichment of the OX40 signaling pathway in proliferating HIV neg GC-Tfh cells, which was upregulated with a p-value closely approaching significance (p = 0.0518) ( Fig 4D ).

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IL6R and IL6ST DEGs were upregulated with ADA-1 versus SEB alone ( Fig 8A ), however, their upregulation did not reach statistical significance ( S4 Table ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.