Inhibition of β-Catenin/CREB Binding Protein Signaling Attenuates House Dust Mite-Induced Goblet Cell Metaplasia in Mice.

Front Physiol · 2021 · PMC8353457 · PMID 34385933

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

Results ICG-001 Decreases HDM-Induced Goblet Cell Metaplasia in vivo Sensitization of mice for 3 days from day 0 to 3 followed by exposure to HDM for 4 days from day 14 to 17 showed a strong trend ( p = 0.06) toward a decrease in the mRNA expression of E-cadherin ( Cdh1 ) compared to PBS-sensitized and PBS-challenged mice.

also in 5,725 other papers

failed to reach statistical significanceno p-value reported

The observed effect of ICG-001 on mucus production is in line with a trend toward a decrease in HDM-induced Muc5ac expression with ICG-001 treatment, which may have failed to reach statistical significance due to the high variation between mice.

also in 6,035 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.