Comprehensive phenotypic and functional analysis of dominant and recessive FOXE3 alleles in ocular developmental disorders.

Hum Mol Genet · 2021 · PMC8369840 · PMID 34046667

Europe PMC DOI

hedged sentences

0.0504

closest p · 1.0× alpha

0.1400

boldest claim

The sentences

approached significanceP = 0.0504so close (0.05 < p ≤ 0.1)

Increased frequency of at least one normal sized eye (typically associated with glaucoma) within the biallelic missense group also approached significance ( P = 0.0504).

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did not reach statistical significanceP = 0.14not close (p > 0.1)

While cataract and lack of corneal opacity were only seen in families with biallelic missense variants, this difference approached but did not reach statistical significance ( P = 0.14 and P = 0.07, respectively).

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