Barely Significant
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Plasma Exchange in Patients With Severe Coronavirus Disease 2019: A Single-Center Experience.

Crit Care Explor · 2021 · PMC8382335 · PMID 34476404

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showed a trendno p-value reported
Finally, another large study showed a trend toward improved survival with the use of PE in critically ill COVID-19 patients with features of a hyperinflammatory syndrome but did not reach statistical significance ( 35 ).

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Only an improvement in body temperature and CRP level was observed in the controls; the latter, however, did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.