New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes.

Front Endocrinol (Lausanne) · 2021 · PMC8385132 · PMID 34456865

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nominally significantno p-value reported

The list of previously mapped loci was here expanded to include nominally significant loci to facilitate pathway enrichment analysis of target genes.

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showed a trendno p-value reported

Two additional results were consistent with a potential role of T2D-eQTL in regulating the 50 identified cis- NEMGs in the context of T2D risk: (1) the 50 cis- NEMGs showed greater differential expression compared to other NEMGs and (2) other NEMGs showed a trend towards significantly decreased expression if their expression levels correlated more highly with the subset of 50 cis- NEMGs.

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