Changes in cell morphology after stretch indicated an increase in MuSC aspect ratio, as MuSCs became more elongated and a negative trend in roundness was noted ( Fig. 2 , G and H ).
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Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche.
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The sentences
We show that MuSCs upregulate Wnt5a mRNA levels in response to PFSS, but the increase did not reach statistical significance.