Does Adding Standard Systematic Biopsy to Targeted Prostate Biopsy in PI-RADS 3 to 5 Lesions Enhance the Detection of Clinically Significant Prostate Cancer? Should All Patients with PI-RADS 3 Undergo Targeted Biopsy?

Diagnostics (Basel) · 2021 · PMC8392157 · PMID 34441270

Europe PMC DOI

hedged sentence

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

a clear trendp = 0.067so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

The differences between the lesion locations did not reach statistical significance, but a clear trend ( p = 0.067), with detection rates of 11.4% vs. 12.5% vs. 42.9% in the peripheral, transition/central zone, and anterior fibromuscular stroma zones, respectively.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.