ABCB1 Does Not Require the Side-Chain Hydrogen-Bond Donors Gln347, Gln725, Gln990 to Confer Cellular Resistance to the Anticancer Drug Taxol.

Int J Mol Sci · 2021 · PMC8395328 · PMID 34445264

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Q725A showed a trend towards being more functional than the wild-type but this did not reach statistical significance and no effect was recorded for Q990A.

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ABCB1 Does Not Require the Side-Chain Hydrogen-Bond Donors Gln<sup>347</sup>, Gln<sup>725</sup>, Gln<sup>990</sup> to Confer Cellular Resistance to the Anticancer Drug Taxol.

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