The Potential Role of Serotonergic Hallucinogens in Depression Treatment.

Life (Basel) · 2021 · PMC8400004 · PMID 34440508

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did not reach statistical significanceno p-value reported

The change in the Quick Inventory of Depressive Symptomatology-Self-Report (QIDS-SR-16) score at 6 weeks was the primary endpoint and was −8 versus −6 in the psilocybin and escitalopram groups, respectively, but this difference did not reach statistical significance.

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approached significanceno p-value reported

There was a significant reduction in depression symptoms immediately post-session, which was sustained and approached significance at a 7-day follow-up.

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