Brain responses during delay discounting in youth at high-risk for substance use disorders.

Neuroimage Clin · 2021 · PMC8414537 · PMID 34479170

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Additionally, [Delayed > BL] activation in the left thalamus showed a trend-level negative association with the lability/negativity ( p = 0.06; see Inline Supplementary Figure 3 ) subscale of the ERC.

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did not reach statistical significanceno p-value reported

The activation pattern in the PIC during delayed choice was high-risk > psychiatric control > healthy control, suggesting an additive marker for risk, with the highest risk associated with the most activation in this region (although note that the difference between high-risk and psychiatric control did not reach statistical significance).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.