Mice with Whole-Body Disruption of AMPK-Glycogen Binding Have Increased Adiposity, Reduced Fat Oxidation and Altered Tissue Glycogen Dynamics.

Consistent with the RER data, individual differences in overall substrate oxidation during light and dark phases or across 24 h did not reach statistical significance ( Figure 2 g,h). 2.3.

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While there was an overall genotype effect of an increased respiratory exchange ratio (RER) in DKI mice versus WT ( Figure 2 d), individual differences in the light phase, dark phase, or 24 h period failed to reach statistical significance ( Figure 2 e).

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