Prognostic significance of human papillomavirus 16 viral load level in patients with oropharyngeal cancer.

Cancer Sci · 2021 · PMC8486212 · PMID 34382311

Europe PMC DOI

hedged sentences

0.0710

closest p · 1.4× alpha

0.2310

boldest claim

The sentences

approached significanceP = .071so close (0.05 < p ≤ 0.1)

The p16 + /HPV DNA − subgroup showed a significantly less favorable PFS compared with the p16 + /HPV DNA high/medium subgroup ( P < .001), and the difference in OS between these two subgroups approached significance ( P = .071).

also in 8,237 other papers

did not reach statistical significanceP = .231not close (p > 0.1)

The p16 + /HPV DNA + group had significantly better PFS than the other three groups: p16 + /HPV DNA − , p16 − /HPV DNA + , and p16 − /HPV DNA − , but the difference in OS did not reach statistical significance between the p16 + /HPV DNA + and p16 + /HPV DNA − groups ( P = .231).

also in 111,027 other papers

an increasing trendno p-value reported

In Japan, studies showed the prevalence rate of HPV in OPSCC cases to be 40%–50% over the last two decades, 16 , 17 suggesting an increasing trend of HPV‐positive OPSCC cases in this region.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.