Comedonecrosis Gleason pattern 5 is associated with worse clinical outcome in operated prostate cancer patients.

Mod Pathol · 2021 · PMC8514328 · PMID 34175896

Europe PMC DOI

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did not reach statistical significanceP = 0.09so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Medium to large solid fields showed a trend towards unfavorable outcome, however this did not reach statistical significance ( P = 0.09).

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did not reach conventional levels of significanceno p-value reported

While the first group also had higher PSA levels (18.8 ng/ml versus 10.1 ng/ml, P = 0.12) and more PLND metastasis (17/78; 21.8% versus 0/12; 0%, P = 0.07) than the latter, this did not reach conventional levels of significance putatively due to a limited number of cases.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.