Starting dose and dose adjustment of non-vitamin K antagonist oral anticoagulation agents in a nationwide cohort of patients with atrial fibrillation.

Sci Rep · 2021 · PMC8526656 · PMID 34667256

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a clear trendno p-value reported

Conversely in AIFA Registry, there was a clear trend towards a reduction of the proportion of patients treated with reduced dose overtime.

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showed a trendno p-value reported

Remarkably, patients on reduced dose in this study showed a trend towards a higher risk of ischemic stroke versus VKA users.

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