Automated Fiber Diameter and Porosity Measurements of Plasma Clots in Scanning Electron Microscopy Images.

For the lupus samples (large pixel size), for which there is a strong trend for SLE samples to have larger fibers compared to the healthy controls, algorithms T6, T5, and S3 (the best algorithms for lower resolution SEM images with larger pixel size), successfully reproduced the manual measurements ( Figure 3 ).

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However, a clear trend was observed between patients and controls in both sample sets.

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