The abovementioned observations were not proven in our study, since the mean HR was 58.6 ± 7.9 beats/minute despite the group allocation and the intergroup differences did not reach statistical significance, although the mean values for TEIBL, LOP, and the total consumption of anesthetics did.
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The sentences
The overall cumulative dose of remifentanil and propofol given failed to reach statistical significance in the SPI guidance and optimized the intraoperative use of TIVA without sparring effect and influence on LOP.