Metabolic profiling of attached and detached metformin and 2-deoxy-D-glucose treated breast cancer cells reveals adaptive changes in metabolome of detached cells.

Sci Rep · 2021 · PMC8560930 · PMID 34725457

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

showed a trendp > 0.05actually significant

In Met, LoDG and MetDG compared to CTRL, hexose showed a trend towards lower levels ( p > 0.05, Fig. 5 ).

also in 53,322 other papers

a weak trendp > 0.05actually significant

There was a weak trend towards higher percentage of dead cells in FloatHiDG and FloatMetDG ( p > 0.05) and the percentage of apoptotic cells was significantly higher in FloatMetDG compared to CTRL ( p < 0.05), but in all cases, the percentage of dead cells was under 10%.

also in 1,404 other papers

a clear trendno p-value reported

While we could not confirm an increase in mitochondrial mass in floating cells compared to their attached counterparts, we observed a clear trend towards higher mitochondrial mass compared to CTRL in both HiDG and MetDG as well as FloatHiDG and FloatMetDG.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.