Genetic variation in NDFIP1 modifies the metabolic patterns in immune cells of multiple sclerosis patients.

2 B), we observed opposite trends in the genotypes in controls and patients: while the minor-allele homozygotes showed a trend to have a lower NDFIP1 expression in MS patients compared to controls, the major allele carriers had a higher expression in MS patients than in controls, a difference that was statistically significant ( p = 0.001).

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In the control population, a trend to lower expression in major-allele carriers was observed when compared to GG homozygotes, although it did not reach statistical significance.

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