Prognostic value of E-Cadherin and its tumor suppressor role in Saudi women with advanced epithelial ovarian cancer.

Libyan J Med · 2021 · PMC8567888 · PMID 34720069

Europe PMC DOI

hedged sentences

0.0090

closest p · 0.2× alpha

0.0600

boldest claim

The sentences

highly significantp < 0.009actually significant

Strikingly, E-CAD protein expression was a highly significant prognosticator of OC patients at the advanced-stages (III, IV) ( p < 0.009, log-rank ) ( Figure 3 ).

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borderline significantp = 0.06so close (0.05 < p ≤ 0.1)

Results: E-CAD protein expression was significantly correlated with OC histological subtype (p < 0.0001), while borderline significant correlations were observed with both tumor grade (p = 0.06) and stage (p = 0.07).

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a clear trendno p-value reported

However, a clear trend of less recurrence is observed in patients with E-CAD expression compared to those with no E-CAD expression ( Figure 2A , Figure 3A ) 4.

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showed a trendno p-value reported

Kaplan-Meier Survival analysis performed on the whole patients’ cohort showed that OC patients with higher membranous E-CAD expression showed a trend of longer survivals than those with no E-CAD expression ( Figure 2A and B).

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