B-cell activating factor BAFF as a novel alert marker for the immunological risk stratification after kidney transplantation.

In contrast, it was seen that patients with BAFF values above the median showed a marked trend towards more acute microvascular inflammation, in particular peritubular capillaritis (p = 0.07) and intimal arteritis (p = 0.09), all of which may be regarded as histopathological signs of AMR (Fig. 2 a and b).

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Also in comparison to the high-risk group, the medium-risk group showed a trend towards an increased incidence of interstitial fibrosis and interstitial atrophy, reaching the level of significance in the biopsies, which were carried out between 31 and 100 days after the transplantation (ci: p = 0.02; ct: p = 0.02).

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