Dynamic Interaction Between Mucosal Immunity and Microbiota Drives Nose and Pharynx Homeostasis of Common Carp (<i>Cyprinus carpio</i>) After SVCV Infection.

At the order level, although the changes in the microbial composition of the nose were moderate except Clostridiales , we observed clearly significant microbial changes in the pharynx, including pathogenic bacteria Burkholderiales and Pseudomonadales , together with beneficial bacteria Clostridiales and Lactobacillales , which further confirmed the diversity of microbial changes between the nose and pharynx in teleost due to geographical differences ( Figures 5E, F ) .

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In olfactory organs, the width of the LP at the tip region (100 μm from the lamellar tip) gradually enlarged from 1 to 14 dpi and showed a trend of recovery at 28 dpi, which all increased significantly compared with the control fish ( Figure 2B ).

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