approached significancep = 0.069
Mice lacking 5-HT 1B R expression showed increased lick rates that approached significance ( Fig. 4C , D ; F 1,9 = 4.3, p = 0.069).
Mice lacking 5-HT 1B R expression showed increased lick rates that approached significance ( Fig. 4C , D ; F 1,9 = 4.3, p = 0.069).
While all mice decreased their lever pressing behavior when the freely available option was evaporated milk compared to chow ( F 1,55 = 106.1, p < 0.0001), mice lacking 5-HT 1B R expression continued pressing at 55% of their baseline rate despite concurrent access to freely available evaporated milk in the operant chamber, while control mice and mice with adult rescue of receptor expression reduced their pressing to 17% and 25% of their baseline rates, respectively (interaction term approaching significance F 2,55 = 2.8, p = 0.069).