Chimeric Antigen Receptor T Cells With Modified Interleukin-13 Preferentially Recognize IL13Rα2 and Suppress Malignant Glioma: A Preclinical Study.

Front Immunol · 2021 · PMC8606595 · PMID 34819930

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.1040

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

WHO grade tended to be associated with whether H-score was 0 or >0, but this did not reach statistical significance ( p = 0.09).

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failed to reach statistical significancep = 0.104not close (p > 0.1)

The median survival time of vehicle-treated mice (81 days) was improved by injection of YYB-103 CAR T cells (97 days), although this difference failed to reach statistical significance due to the small number of treated mice ( p = 0.104, log rank test) ( Figure 3F ).

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