However, the overall pattern of overlapping genes as well as the direction of correlation did not reach statistical significance (Fisher’s exact test, p ≥ 0.05).
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Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.
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It is also of interest that while they did not reach significance, all genes (with the exception of ARO8 ) involved in Lys biosynthesis showed a trend for decreased expression in long-lived strains ( Supplementary file 2 ).