Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1.

Cells · 2021 · PMC8616524 · PMID 34831181

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Atrial CF Il6 mRNA levels showed a trend towards an increase at 4 h of FXa ( p = 0.06).

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failed to reach statistical significanceno p-value reported

Similarly, the FXa-induced increase in CCL2 expression was lower upon F2R silencing, although this effect failed to reach statistical significance.

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