What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 2: Clinic-Pathologic Correlations.

Cells · 2021 · PMC8618408 · PMID 34831388

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showed a trendno p-value reported

[ 75 ] found that neoadjuvant androgen deprivation therapy (neo-AAPL; n = 44) was associated with reduced CD8+ TILs; these PCs showed a trend toward decreased PD-L1 expression as compared to untreated tumors (7% vs. 21%).

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did not reach statistical significanceno p-value reported

Some studies [ 42 , 79 ] reported that PD-L1 positivity in tumor cells did not reach statistical significance for predicting BCR or clinical failure, but there was a trend toward a negative association between PD-L1 expression and BCR ( n = 402; p = 0.078).

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