Inhibition of G-protein signalling in cardiac dysfunction of intellectual developmental disorder with cardiac arrhythmia (IDDCA) syndrome.

Baseline ECG parameters were not different among Gnb5 +/+ , Gnb5 +/– and Gnb5 –/– animals, except for HR in knocked-out animals that showed a trend toward higher values (online supplemental figure S2C, minimum and maximum HR values registered in wild-type were 313 and 741 beats/min, while lowest and greatest HR values in knockout were 349 and 744 beats/min, significance varying between p=1.28E-04 and p=0.9971, over 36 daylight time points).

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Nominally significant enriched terms were retained for results interpretation.

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