Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans.

Sci Rep · 2021 · PMC8654850 · PMID 34880287

Europe PMC DOI

hedged sentences

0.0270

closest p · 0.5× alpha

0.1390

boldest claim

The sentences

nominally significantp = 0.027actually significant

However, a few of its linkage disequilibrium (LD) proxies (r 2 > 0.77 in Europeans) were nominally significant in the meta-analysis (results for the leading variant rs9271588, OR [95% CI] = 1.20 [1.02–1.41], p = 0.027).

also in 7,732 other papers

did not reach statistical significancep = 0.139not close (p > 0.1)

Mapping each nucleotide position within the altered codon indicated that E57Q corresponds to rs10093, which did not reach statistical significance in our study (meta-analysis OR [95%CI] = 1.13 [0.96–1.33], p = 0.139).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.