Comparison of Drug-Coated Balloon Angioplasty vs. Drug-Eluting Stent Implantation for Drug-Eluting Stent Restenosis in the Routine Clinical Practice: A Meta-Analysis of Randomized Controlled Trials.

Front Cardiovasc Med · 2021 · PMC8671700 · PMID 34926617

Europe PMC DOI

hedged sentences

0.0003

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

a significant trendp = 0.0003actually significant

However, subsequent subgroup analysis demonstrated a significant trend toward an increment in MLD (MD = −0.25 mm, 95 CI −0.38 to −0.11 mm, p = 0.0003; I 2 = 0%, p = 0.70, Figure 2A ) was observed in the everolimus-eluting stents (EES) group.

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a strong trendp = 0.08so close (0.05 < p ≤ 0.1)

In the subgroup analysis, a strong trend toward a decrease in TLR (RR = 1.36, 95% CI 0.96–1.91, p = 0.08; I 2 = 0%, p = 0.56, Figure 4 ) was even noted in paclitaxel-eluting stent (PES) group, although this difference was not statistically significant compared to DCB.

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marginally significantno p-value reported

Moreover, this trend still persisted when we compared PES with DCB, but it was marginally significant.

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