HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.

Elife · 2021 · PMC8676326 · PMID 34608862

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.1100

boldest claim

The sentences

did not reach statistical significancep=0.07so close (0.05 < p ≤ 0.1)

In contrast, the median CD4 T cell count across all study visits was lower in PLWH (277 versus 339), although this difference did not reach statistical significance (p=0.07).

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showed a trendp=0.11not close (p > 0.1)

We also analyzed the time of SARS-CoV-2 clearance as a function of CD4 count and HIV status and found that while participants with a low CD4 count (<200) showed a trend of longer time to SARS-CoV-2 clearance (p=0.11), HIV viremia had no effect ( Figure 1—figure supplement 5 ).

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