Low-Salt Diet Attenuates B-Cell- and Myeloid-Cell-Driven Experimental Arthritides by Affecting Innate as Well as Adaptive Immune Mechanisms.

In CIA we also observed reduced joint inflammation and less cartilage damage upon NaCl restriction; however, histological scores between groups did not reach statistical significance ( Supplementary Figure 2 ).

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In comparison to HS-diet, NaCl restriction showed a trend toward a reduction of the relative expression of IFN-gamma mRNA at day 20, whereas IFN-gamma mRNA expression was similar in both groups at day 47 ( Table 2 ) .

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