Dose-response effects of alcohol on biochemical markers of bone turnover in non-human primates: Effects of species, sex and age of onset of drinking.

Bone Rep · 2022 · PMC8683688 · PMID 34977281

Europe PMC DOI

hedged sentences

0.4100

closest p · 8.2× alpha

0.4100

boldest claim

The sentences

a significant trendp = 0.41not close (p > 0.1)

However, we did not observe a significant trend in the osteocalcin to CTX ratio in response to ethanol in males of either species (rhesus: 0.4, p = 0.41; cynomolgus: 0.2, p = 0.71; Fig. 4 C).

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a strong trendno p-value reported

We reported that 12 months of chronic ethanol consumption in male rhesus macaques resulted in a strong trend for a reduction in osteocalcin and reduced cancellous bone formation ( Kahler-Quesada et al., 2019 ).

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