DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases.

Cancer Imaging · 2021 · PMC8684660 · PMID 34924031

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did not reach statistical significanceno p-value reported

However, the perfusion-related parameter changes (f, D* and fD*) did not reach statistical significance.

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highly significantno p-value reported

Interestingly, the highly significant therapeutic effects observed for DCE-MRI parameters such as K trans , EF and KEF following Regorafenib treatment were not matched by changes in the perfusion-related IVIM-DWI parameters (f, D* or fD*; none reached significance).

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failed to reach statistical significanceno p-value reported

The highest correlation between DCE-MRI and IVIM-DWI methods was moderate ( r =0.67, P <0.001) and correlated K trans and fD* parameters, even though changes in fD* failed to reach statistical significance when measured before and after treatment.

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